She will play number 14 seed Daniela Hantuchova of Slovakia, who wore down number 12 Li Na of China 7-5 4-6 6-1.
The Indian sensation scored a second successive upset, disposing off the fourth seeded Swiss ace at the Bank of the West of Classic.
Lindsay Davenport was one of seven seeds to advance but four went out, including number three Daniela Hantuchova, fifth-seeded Patty Schnyder and Austrian Sybille Bammer, in the second round of the Amelia Island Championships.
The Indian ace will meet top seed Anna Chakvetadze of Russia in the summit clash.
Second seed Jelena Jankovic cruised into the U.S. Open semi-finals with a 6-1 6-4 win over 29th seed Sybille Bammer on Tuesday.
Top-seeded Serb Ana Ivanovic withdrew from the Qatar Open on Thursday after injuring her left ankle beating Olga Govortsova of Belarus the previous day.
Second and third seeds Jelena Jankovic and Daniela Hantuchova were sent spinning from the Amelia Island tennis championship on Friday.
The defending champion will play eighth seed Marion Bartoli of France.